In order to provide a reference for clinical research and prescription of insomnia by analyzing the distribution of syndrome types and medication rules of TCM, treating insomnia from the perspective of heart. We retrieved the "literatures on treating insomnia of the heart" from CNKI and established the database from December 2011 to December 2021. And we statistically analyzed the literature types, syndrome type distribution, and medication rule. Resultly, among the 828 literatures included, 718 literatures related to clinical research were the most, accounting for 87% of the total, involving a total of 24 syndrome types, among which, heart spleen deficiency (417 cases, 52%) and disharmony between heart and kidney (256 cases, 32%) accounted for the highest proportion. The most commonly used prescription for insomnia with heart spleen deficiency was spleen-restored decoction. The most frequently used drugs were semen ziziphi spinosae, Astragalus membranaceus, and Angelica sinensis. The most commonly used prescription for disharmony between heart and kidney insomnia was self-made prescription, and the most frequently used drugs were Coptis chinensis, cinnamon, and semen ziziphi spinosae. In conclusion, treating insomnia of the mind has a rich theoretical and clinical basis and can be dialectically used in clinics.

Lingli Fu, Zucheng Han. Literature Analysis of Treating Insomnia from the Heart. International Journal of World Medicine (2023), Vol. 4, Issue 3: 55-62. https://doi.org/10.38007/IJWM.2023.040307.

[1] Zhang Peng. Zhao Zhongxin. Interpretation of "Guidelines for the diagnosis and treatment of adult insomnia in China". Chinese Journal of Contemporary Neurology and Neurosurgery, 2013, 13(5): 363-367.

[2] Li Na. A cross-sectional study on the relationship between lifestyle, chronic disease history and sleep status in adults. Chinese Medical University, 2020.

[3] Zheng B, Yu C, Lv J, et al. Insomnia symptoms and risk of cardiovascular diseases among 0.5 million adults: A 10-year cohort. Neurology. 2019; 93(23):e2110-e2120.

[4] Hu Y, Yan Z, Fu Z, et al. Associations of Insomnia with Hypertension and Coronary Artery Disease among Patients with Type 2 Diabetes Mellitus. Front Cardiovasc Med. 2021; 8:730654.

[5] Shi Mengmeng, Liu Chunfang, Guo Yuehan, et al. Literature Analysis of Adverse Reactions Induced By Zolpidem. Drugs & Clinic, 2019, 34(04):1252-1256.

[6] Zhang Boli, Wu Mianhua. Internal Medicine. Beijing: China Traditional Chinese Medicine Publishing House, 2017.

[7] Li Candong. Diagnostics of Traditional Chinese Medicine. Beijing: China Traditional Chinese Medicine Press, 2016.

[8] National Pharmacopoeia Committee. Chinese Pharmacopoeia. Beijing: China Pharmaceutical Science and Technology Press, 2020. 

[9] Liu Zonglian, Kang Ling, Gao Zutao. Gao Ronglin's experience in treating insomnia from the heart. Chinese Journal of Basic Medicine in Traditional Chinese Medicine, 2008(10):753-754.

[10] Li Haihong. Treatment of insomnia from the heart-Liu Jizu's treatment of 'insomnia' characteristics. Xinjiang Journal of Traditional Chinese Medicine, 2014, 32(05):52-54.

[11] Liu Yuan, Xiao Jiabin, Xiao Yangchun. Effect of Jiaotai Pills on Sleep Progress and Sleep Structure of Heart-Kidney Disjoint Type Elderly Patients With Insomnia. World Journal of Integrated Traditional and Western Medicine, 2021, 16(07):1304-1307.

[12] Zhang Yong, Zhao Qiang. Clinical observation on the treatment of insomnia with deficiency of heart and spleen by Yunzhou Tuifu method. China Journal of Traditional Chinese Medicine and Pharmacy, 2021, 36(10):6250-6253.

[13] Niu Qiyun, Miao Zhiguo. Clinical observation of acupuncture at back acupoints in the treatment of senile insomnia with heart and spleen deficiency syndrome. Chinese Journal of Gerontology, 2021, 41(22):5024-5027.

[14] Liu Yanting, Cai Zhongming, Li Yaoqian. Experience in insomnia diagnosis and treatment. Clinical Journal of Chinese Medicine, 2018, 10(33):18-19.

[15] Wang Jian. Basic Theory of Traditional Chinese Medicine. Beijing: China Traditional Chinese Medicine Publishing House, 2016: 10-11.

[16] Ma Jie, Li Feng, Song Yuehan, et al. Literature study of treating insomnia from liver. China Journal of Traditional Chinese Medicine and Pharmacy, 2012, 27(04):1076-1080.

[17] Chen Liyuan, Ye Tianyuan, Qi Dongmei, et al. Modern Clinical Applications and Type of Disease Prevention and Treatment of Guipitang:A Review. Chinese Journal of Experimental Traditional Medical Formulae, 2021, 27(15):219-226.

[18] Li Candong. diagnostics of Chinese medicine. Beijing: China Traditional Chinese Medicine Press, 2016: 202-203.

[19] Zhu Jiayi, Dong Hongli. Research of Jiaotai Pill Mechanism in Treating Insomnia of Heart-kidney Disharmony Type. Clinical Journal of Traditional Chinese Medicine, 2021, 33(11):2258-2261.