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International Journal of Health and Pharmaceutical Medicine, 2020, 1(2); doi: 10.38007/IJHPM.2020.010202.

Oral Chinese Medicine Combined with High Frequency Electrotome on T Cell Subsets in Condyloma Acuminatum Lesions under Optical Microscope

Author(s)

Abbas Khosravi

Corresponding Author:
Abbas Khosravi
Affiliation(s)

Ecole Normale Superieure, Paris, France

Abstract

In recent years, the incidence rate of condyloma acuminatum in China has also increased year by year, ranking second in STD, followed by gonorrhea. Condyloma acuminatum and genital cancer have a special relationship, so more and more people pay attention to it. At present, the treatment of condyloma acuminatum is based on clearing the wart, emphasizing the regulation of patient's immune function and active development of effective preventive vaccine. The purpose of this study is to prove that oral Chinese medicine combined with high frequency electrotome has clinical effect on condyloma acuminatum, and to explore the influence of this research method on T cell subsets in condyloma acuminatum lesions. In this study, 90 cases of anogenital Condyloma Acuminatum Patients Treated from June 2018 to October 2019 were selected as the research object, and three groups of control experiments were set up, which were the control group, the oral Chinese medicine treatment group and the high-frequency electrotome group. The results showed that after a month of treatment, the adverse symptoms of anorexia and fatigue were significantly improved, and the difference was statistically significant (P < 0.05). The most important factor affecting the recurrence of condyloma acuminatum was abnormal T cell subsets, accounting for 34%, followed by drinking, accounting for 23%, and the least influencing factor was staying up late, accounting for only 8%. After one month treatment, the ratio of CD4 + / CD8 + increased from 1.02 to 1.26, the ratio of oral Chinese medicine increased from 0.93 to 1.23, while the ratio of control group decreased from 0.82 to 0.68.

Keywords

Optical Microscope, Oral Chinese Medicine, High Frequency Electrotome, Condyloma Acuminatum, T Cell Subsets in Skin Lesions

Cite This Paper

Abbas Khosravi. Oral Chinese Medicine Combined with High Frequency Electrotome on T Cell Subsets in Condyloma Acuminatum Lesions under Optical Microscope. International Journal of Health and Pharmaceutical Medicine (2020), Vol. 1, Issue 2: 13-24. https://doi.org/10.38007/IJHPM.2020.010202.

References

[1] Zhang, L., Li, X., Liu, X., Gao, Y., & Tang, Q. (2019). “Treatment of Multi-Position Condyloma Acuminatum with Topical Co2 Laser Combined Photodynamic Therapy – Report of 6 Cases”, Photodiagnosis and Photodynamic Therapy, 25(MAR.),pp. 436-439. DOI; 10.1016/j.pdpdt.2019.01.030

[2] Cong, X., Sun, R., Zhang, X., Wang, Y., Wang, L., & Yu, Y. (2016).” Correlation of Human Papillomavirus Types with Clinical Features of Patients with Condyloma Acuminatum in China”, International journal of dermatology, 55(7),pp. 775-780.

[3] Chen,Quan, Yang,Ridong, Gao,Aili, Zhong,Daoqing, & Zhu,Huilan. (2017). “Efficacy of Fulguration Combined with Imiquimod Cream on Condyloma Acuminatum, and The Effect on Immune Functions and Serums Levels of Il-2 And Il-10”, Experimental and therapeutic medicine, 14(1),pp. 131-134. DOI: 10.3892/etm.2017.4445

[4] Ye Y, Sun XZ, & Feng JS. (2015). “Woman with Rectal Condyloma Acuminatum: A Case Report”, International Journal of Clinical & Experimental Medicine, 8(4),pp. 6365-8.

[5] Kurita, Y., Higurashi, T., Komiya, Y., Umezawa, S., & Nakajima, A. . (2016). “Anorectal Condyloma Acuminatum Diagnosed by Image Enhanced Endoscopy, Treated by Endoscopic Submucosal Dissection”, Progress of Digestive Endoscopy, 88(1), pp.160-161.

[6] Altamirano, Víctor, Romero, P., Palacios, I., Inada, N., & Bagnato, V. S. . (2015). “Treatment of Condyloma Acuminatum Using Methyl-Aminolaevulinic Acid for Introduce A Medical Guideline on Health Public System”, Photodiagnosis & Photodynamic Therapy, 12(3), pp.342-343. DOI: 10.1016/j.pdpdt.2015.07.073

[7] Hamed, A. (2015). “Electrocautery Resection, Shaving with A Scalpel, and Podophyllin: A Combination Therapy for Giant Condyloma Acuminatum”, The World Journal of Men's Health, 33(1), pp.39-.

[8] Guttadauro A, Chiarelli M, Macchini D, Frassani S, Maternini M, & Bertolini A. (2015). “Circumferential Anal Giant Condyloma Acuminatum: A New Surgical Approach”, Diseases of the Colon & Rectum, 58(4), pp.e49.

[9] Hirahara K, & Nakayama T. (2016). “Cd4+ t-Cell Subsets in Inflammatory Diseases: Beyond The Th1/Th2 Paradigm”, International Immunology, 28(4), pp.163.

[10] Czarnowicki, T., Malajian, D., Shemer, A., Fuentes-Duculan, J., Gonzalez, J., & Suárez-Fari?as, Mayte, et al. (2015). “Skin-Homing and Systemic t-Cell Subsets Show Higher Activation in Atopic Dermatitis Versus Psoriasis”, Journal of Allergy & Clinical Immunology, 136(1), pp.208-211. DOI: 10.1016/j.jaci.2015.03.032

[11] Muller, L., Mitsuhashi, M., Simms, P., Gooding, W. E., & Whiteside, T. L. . (2016). “Tumor-Derived Exosomes Regulate Expression of Immune Function-Related Genes in Human T Cell Subsets”, Rep, 6(1), pp.20254.

[12] He, J., Zhang, X., Wei, Y., Sun, X., & Li, Z. (2016). “Low-Dose Interleukin-2 Treatment Selectively Modulates Cd4(+) t Cell Subsets in Patients with Systemic Lupus Erythematosus”, Nature Medicine, 22(9), pp.991-993.