Chronic renal failure (CRF) has become one of the chronic diseases that seriously damage human health worldwide. For the prevention and treatment of this disease, Chinese medicine has certain advantages due to its uniqueness. The diagnosis and treatment of chronic renal failure from the perspective of the combination of western medicine diseases and TCM syndrome types reflects the characteristics of TCM syndrome differentiation. The combination of disease and syndrome in animal models is widely needed in the connection between TCM clinical and basic experiments. Therefore, the successful construction of an animal model under the combination of disease and syndrome that conforms to the clinical characteristics of the disease has certain advantages for people to further understand the etiology and pathogenesis of the disease. This article reviews the research progress of CRF experimental animal models under the mode of combination of disease and syndrome, in order to provide a basis for the preparation of an animal models for TCM experimental research.

Lei Xu, Yiying Wu, Wenjing Wang, Hang Li and Yanlong Zhao. Research Progress of Experimental Animal Model of Chronic Renal Failure in Combination of Disease and Syndrome. International Journal of Public Health and Preventive Medicine (2022), Vol. 3, Issue 4: 9-18. https://doi.org/10.38007/IJPHPM.2022.030402.

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