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International Journal of Public Health and Preventive Medicine, 2022, 3(2); doi: 10.38007/IJPHPM.2022.030203.

Correlation between Changes of Intestinal Flora in Patients with Rectal Cancer and Nutritional Supplementation of Immune Function Food


Ruiliang Ling

Corresponding Author:
Ruiliang Ling

Shandong Jiaotong University, Weihai, China


Rectal cancer is a malignant tumor of the digestive system with a high mortality rate. At present, the most important way to treat rectal cancer is surgical resection. However, radiotherapy and chemotherapy, drug therapy, and dietary supplements are often used as adjuvant treatments. The imbalance of intestinal flora is one of the causes of rectal cancer. Enhancing the immune function of the body can improve the imbalance of intestinal flora. The purpose of this article is to explore the impact of immune function food and nutritional supplementation on the changes of intestinal flora in patients with rectal cancer and the mechanism. 20 rectal cancer patients included in our hospital in 2019 were selected as the research objects, and they were randomly divided into control group and observation group. In the control group, patients in the control group received routine nutritional intervention, and the patients in the observation group received immune function food nutritional supplements. After 10 days, feces of the two groups were extracted to detect changes in the intestinal flora, expression levels of tumor cell inflammatory factors and immune response indicators. The results showed that the number of bifidobacteria and enterococci in the observation group were 24.6% and 19.7% higher than those in the control group, the expression level of tumor inflammatory factors in the observation group was decreased by 27.2%, and the immune response index was increased by 33.6% compared with the control group. It can be seen that nutritional supplementation of immune function food can improve the imbalance of intestinal flora in patients with rectal cancer, reduce inflammatory response and improve the immunity of patients.


Rectal Cancer Patients, Changes in Intestinal Flora, Immune Function, Food Supplement

Cite This Paper

Ruiliang Ling. Correlation between Changes of Intestinal Flora in Patients with Rectal Cancer and Nutritional Supplementation of Immune Function Food. International Journal of Public Health and Preventive Medicine (2022), Vol. 3, Issue 2: 34-46. https://doi.org/10.38007/IJPHPM.2022.030203.


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