Welcome to Scholar Publishing Group

International Journal of Multimedia Computing, 2022, 3(2); doi: 10.38007/IJMC.2022.030204.

Computer Simulation Modification and Simulation of the Mechanism of Immunosuppressive Tumors


Tran Anh Tuan and Emanuela Guido

Corresponding Author:
Tran Anh Tuan

University of Helsinki, Finland


In recent years, with the rapid development of medical imaging, computer and hemodynamics theory and technology, it has become a hotspot to use computer simulation technology to simulate the mechanism of immunosuppressive tumors. The simulation results tend to be real tumors of human body, and play an important role in revealing the mechanism of the occurrence and evolution of immunosuppressive tumors. Effect. In this paper, a computer simulation model for the growth of tumors in normal cell tissues is established by studying the mechanism of immunosuppressive effect on tumors.The simulation design of computer simulation of tumors is proposed.


Body Immunity, Computer Simulation of Tumors, Tumor, Tumor Simulation

Cite This Paper

Tran Anh Tuan and Emanuela Guido. Computer Simulation Modification and Simulation of the Mechanism of Immunosuppressive Tumors. International Journal of Multimedia Computing (2022), Vol. 3, Issue 2: 23-28. https://doi.org/10.38007/IJMC.2022.030204.


[1] Lee J H, Han I H, Choi B K, et al. Virtual Preoperative Simulation for Excision of Spinal Tumors: Surgeon Processing of Medical Computer-Assisted Design Software:. Korean Journal of Spine, 2017, 14(4):170-174. https://doi.org/10.14245/kjs.2017.14.4.170

[2] Das S, Paul S. Computer Simulation Studies of the Mechanism of Hydrotrope-Assisted Solubilization of a Sparingly Soluble Drug Molecule. Journal of Physical Chemistry B, 2016, 120(14):3540-3550. https://doi.org/10.1021/acs.jpcb.5b11902

[3] Basler L, Andratschke N, Ehrbar S, et al. Modelling the immunosuppressive effect of liver SBRT by simulating the dose to circulating lymphocytes: an in-silico planning study. Radiation Oncology, 2018, 13(1):10. https://doi.org/10.1186/s13014-018-0952-y

[4] Park S W, Deyoung A D, Dhumal N R, et al. Computer Simulation Study of Graphene Oxide Supercapacitors: Charge Screening Mechanism. Journal of Physical Chemistry Letters, 2016, 7(7):1180-1186. https://doi.org/10.1021/acs.jpclett.6b00202

[5] Welter M, Rieger H. Computer Simulations of the Tumor Vasculature: Applications to Interstitial Fluid Flow, Drug Delivery, and Oxygen Supply. Systems Biology of Tumor Microenvironment. 2016. https://doi.org/10.1007/978-3-319-42023-3_3

[6] Li H, Lan L, Sennett C, et al. SU-E-J-248: Contributions of Tumor and Stroma Phenotyping in Computer-Aided Diagnosis. Medical Physics, 2015, 42(6Part11):3323-3323. https://doi.org/10.1118/1.4924334

[7] Welter M, Rieger H. Computer Simulations of the Tumor Vasculature: Applications to Interstitial Fluid Flow, Drug Delivery, and Oxygen Supply. Advances in Experimental Medicine & Biology, 2016, 936:31. https://doi.org/10.1007/978-3-319-42023-3_3

[8] Ewing A D, Houlahan K E, Hu Y, et al. Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection. Nature Methods, 2015, 12(7):623-630. https://doi.org/10.1038/nmeth.3407

[9] Azarnoush H, Alzhrani G, Winkler-Schwartz A, et al. Neurosurgical virtual reality simulation metrics to assess psychomotor skills during brain tumor resection. International Journal of Computer Assisted Radiology & Surgery, 2015, 10(5):603-618. https://doi.org/10.1007/s11548-014-1091-z

[10] Lashin S A, Mamontova E A, Matushkin Y G, et al. Mechanisms of the formation and propagation of sociobiological interactions: a computer simulation study. Russian Journal of Genetics Applied Research, 2015, 5(6):672-678. https://doi.org/10.1134/S2079059715060040

[11] Sun Q, Tang P, Zhao L, et al. Mechanism and structure studies of cinnamaldehyde/cyclodextrins inclusions by computer simulation and NMR technology.. Carbohydrate Polymers, 2018:S0144861718304417. https://doi.org/10.1016/j.carbpol.2018.04.055

[12] Minkin V I, Starikova A A. Computer simulation of the isomerization mechanism and spectral characteristics of spiro[1,3,4]oxadiazines. Russian Chemical Bulletin, 2016, 65(1):40-46. https://doi.org/10.1007/s11172-016-1262-x

[13] Kasaie P, Kelton W D, Ancona R M, et al. Lessons Learned from the Development and Parameterization of a Computer Simulation Model to Evaluate Task Modification for Healthcare Providers.. Academic Emergency Medicine, 2017. https://doi.org/10.1111/acem.13314

[14] Stishkov Y K, Bogdanov D V. Computer simulation of the injection mechanism of initiation of EHD flows in liquids with a higher level of low-voltage conductivity. Surface Engineering & Applied Electrochemistry, 2017, 53(1):27-33. https://doi.org/10.3103/S1068375517010148