In the past few decades, the continuous development of early neonatal monitoring and treatment technology has improved the early survival rate of premature babies and babies born with low weight and high quality. However, the incidence of neonatal necrotizing enterocolitis has not decline. Therefore, it is necessary to actively carry out prevention and surgical treatment based on neonatal necrotizing enterocolitis. The purpose of this article is to discuss the prevention and surgical treatment of neonatal necrotizing enterocolitis. 140 neonates with neonates admitted from October 2013 to October 2019 were selected, and NEC patients were divided into control and in the experimental group, preventive and surgical treatments were performed to observe their effects. The results of the study show that the control group defaults to a group with a fasting time of 0 days. The number of people is 70. There are 60 cases of infants with feeding intolerance, accounting for 85.7%, and the experimental components are 1-7. 8-14, 15-21 three cases, a group of 1-7 days of fasting time, the number of 27 people, feeding intolerance of 11 cases of newborns, accounting for 40.7%. It can be seen that the prevention and surgical treatment based on neonatal necrotizing enterocolitis is of great significance to the health of newborns.

Harald Klempe. Prevention and Surgical Treatment of Neonatal Necrotizing Enterocolitis. International Journal of Public Health and Preventive Medicine (2021), Vol. 2, Issue 3: 49-61. https://doi.org/10.38007/IJPHPM.2021.020305.

[1] Lim, J, C, Golden, J, M, & Ford, H, R. (2015). “Pathogenesis of Neonatal Necrotizing Enterocolitis”, Pediatric Surgery International, 31(6), 509-518. DOI: 10.1007/s00383-015- 3697-9

[2] Aimei, Z. (2015). “Co-word Analysis of Research Trends on Neonatal Necrotizing Enterocolitis”, Journal of Clinical Pediatrics, 33(1), 78-82. DOI: 10.3969/j.issn.1000-3606. 2015.01.020

[3] Yin, Y, Qin, Z, Xu, X, Liu, X, Zou, H, & Wu, X. (2019). “Inhibition of Mir‐124 Improves Neonatal Necrotizing Enterocolitis Via an Mypt1 and Tlr9 Signal Regulation Mechanism”, Journal of Cellular Physiology, 234(7), 10218-10224. DOI: 10.1002/jcp.27691

[4] Patil Basavaraj, Bhimalli Shivanand, & Nagarjuna Chadalavada. (2017). “Neonatal Necrotizing Enterocolitis - a Study of Clinical Profile and Outcome”, Journal of Evolution of Medical & Dental Sciences, 6(1), 7-9. DOI: 10.14260/Jemds/2017/3

[5] Miriam García Gonzalez, Beloy, I,C, Alba Gómez Dovigo, Fortes, L, M, & Jesús Caramés Bouzán. (2017). “Negative Pressure wound Therapy for a Complicated Abdominal Laparotomy in Neonatal Necrotizing Enterocolitis: a Case Report”, Ostomy/wound Management, 63(6), 34-38.

[6] Gomes Rúdnei de Oliveira Luciano, Ricardo, A, N, Guimares Neto José de Freitas, Porto, N, A, Souza, M, E, F, D, & Martins José Luiz. (2017). “Neonatal Necrotizing Enterocolitis Rat Model Attenuated by a Remote Ischemic Preconditioning in the Pregnant”, Acta Cirurgica Brasileira, 32(3), pp.236-242.

[7] Krediet, TG, van Lelyveld, N, Vijlbrief, DC, Fleer, A, Gerards, LJ, & Brouwers, H. (2015). “Microbiological Factors Associated with Neonatal Necrotizing Enterocolitis”, Acta Pædiatrica, 92(10), 1180-1182. DOI: 10.1111/j.1651-2227.2003.tb02481.x

[8] Li, Q,P, Yu, J, L, Hu, K, He, Y, & Ai, Q. (2018). “Protective Effect of Sodium Butyrate on the Neonatal Mouse Model of Necrotizing Enterocolitis”, Medical Journal of Chinese People's Liberation Army, 43(3), 201-205. DOI: 10.11855/j.issn.0577-7402.2018.03.04

[9] Steppberger, K, Meyer-Henn, C, Falkenberg, C, Schuster, V, Rodloff, A, C, & Kiess, W. (2017). “Necrotizing Enterocolitis Incidence, Characteristics, and Outcomes in Neonatal down Syndrome Patients”, American Journal of Perinatology, 34(13), 1368-1374. DOI: 10.1055/s- 0037-1603688

[10] Gephart, S, M, & Quinn, M, C. (2019). “Relationship of Necrotizing Enterocolitis Rates to Adoption of Prevention Practices in Us Neonatal Intensive Care Units”, Advances in Neonatal Care, 19(4), 321-332. DOI: 10.1097/ANC.0000000000000592

[11] Naberhuis, J, Wetzel, C, & Tappenden, K, A. (2016). “A Novel Neonatal Feeding Intolerance and Necrotizing Enterocolitis Risk–Scoring Tool is Easy to Use and Valued by Nursing Staff”, Advances in Neonatal Care, 16(3), 239-244. DOI: 10.1097/ANC.0000000000000250

[12] Betül Siyah Bilgin, Terek, D, Özge Altun Köroğlu, Yalaz, M, & Nilgün Kültürsay. (2016). “Evaluation of Incidence and Characteristics of Necrotizing Enterocolitis in Neonatal Intensive Care Unit”, Journal of Clinical Research in Pediatric Endocrinology, 3(4), 196-202.