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International Journal of Public Health and Preventive Medicine, 2021, 2(3); doi: 10.38007/IJPHPM.2021.020302.

Fatigue Exercise to Regulate the Heart Rate of Parasympathetic Nerve in Normal and Obese Rats


Yao Li

Corresponding Author:
Yao Li

Zunyi Medical University, Guizhou, China


Peripheral nerve injury is very easy to lead to the central nervous system pathways of the human body produce significant changes, and sports training in promoting the recovery of the motor function after the central nerve injury plays a specific role in promoting. The purpose of this study was to investigate the effects of fatigue exercise on parasympathetic heart rate regulation in normal and obese rats. In the experimental study in this paper, normal rats were taken as experimental objects, and the reflex sensitivity of various nerve and heart rate functions was observed under the moderate intensity for 14 weeks as the research indicators, and the difference between the exercise group and the experimental control rats was compared to make a determination. The experimental data in this paper showed that systolic blood pressure (SBP) and diastolic blood pressure (DBP) did not change significantly in the aerobic training group compared with the quiet control group and the fatigue training group, but heart rate (HR) significantly decreased (P<0.05), and the peak left indoor pressure (LVSP) and the maximum rate of left indoor pressure rise (±dP/DT Max) were significantly increased (P<0.05). The expression of left ventricular cholinergic nerve and M2 receptor was significantly up-regulated (P<0.05). The experimental results showed that compared with the control group, the rats in the exercise group had hypertrophy of myocardium, increased cardiac pump strength, sympathetic arterial pressure reflex sensitivity and vagal nerve mediated arterial pressure reflex sensitivity. What is affected in this response is variability in cardiac sympathetic tone and increased variability in cardiac vagal tone. Long-term aerobic exercise can improve the capacity of cardiovascular autonomic regulation, which can make the coordination and conflict between sympathetic and parasympathetic nerves set up a new balance relationship at a higher level of function.


Sports Training, Fatigue Training Section, Quiet Control Group, Sympathetic Nervous

Cite This Paper

Yao Li. Fatigue Exercise to Regulate the Heart Rate of Parasympathetic Nerve in Normal and Obese Rats. International Journal of Public Health and Preventive Medicine (2021), Vol. 2, Issue 3: 13-23. https://doi.org/10.38007/IJPHPM.2021.020302.


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