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International Journal of Public Health and Preventive Medicine, 2021, 2(4); doi: 10.38007/IJPHPM.2021.020401.

Correlation between plasma D-Dimer levels and Clinicopathological Characteristics of Cervical Cancer


Lihua Zhang, Yuanyuan Zhao, Li Li and Huadong Xin

Corresponding Author:
Huadong Xin

The Second Department of Gynaecology, Central Hospital of City Handan, Handan 056001, Hebei, China


To investigate the Correlation between plasma D-Dimer levels and Clinicopathological Characteristics of Cervical Cancer. because Plasma D-Dimer levels were determined using immunoturbidimetry in the three groups of cervical cancer, IN and healthy persons, because and detect the distinction among them. To analyzed the relationship among plasma D-Dimer levels and the invasion, metastasize of cervical cancer further. Plasma D-Dimer levels of the group of cervical cancer had significantly higher than those of CIN and healthy control groups (χ2=13.5436, P﹤0.005;χ2=15.7082, P﹤0.005,respectively),and then plasma D-Dimer levels had not statistically significant differences compared CIN with healthy control group(χ2=0.0016, P>0.05). Plasma D-Dimer levels was positively rank-correlated with tumor diameter, lymph node metastasis, numbers and proportion of metastatic nodes(P<0.05),but no correlation with clinical stage, histological grades, infiltrative depth of muscle, tumor embolus of vessel, latero-uterus infiltration and encroachment of corpus uteri(P>0.05). Plasma D-Dimer levels were much higher in patients with cervical cancer than those of nontumors, which was distinctively associated with tumor diameter, lymphnode metastasis (P<0.05). It is suggested that plasma D-Dimer levels could be play an important role in the invasion and transfer process of cervical cancer.


Cervical Cancer, D-Dimer, Clinicopathological Characteristics

Cite This Paper

Lihua Zhang, Yuanyuan Zhao, Li Li and Huadong Xin. Correlation between plasma D-Dimer levels and Clinicopathological Characteristics of Cervical Cancer. International Journal of Public Health and Preventive Medicine (2021), Vol. 2, Issue 4: 1-7. https://doi.org/10.38007/IJPHPM.2021.020401.


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