Guangdong Medical University, Dongguan, China
Breast cancer has become one of the malignant tumors with the highest incidence in the world. Malignant tumor is a disease that seriously threatens human health. Surgical treatment is difficult to achieve the ideal effect on advanced malignant tumors with extensive metastasis and recurrence. Based on the above background, the purpose of this article is to study the effect of sports on the curative effect of the drug-loaded nanoparticle drug delivery system against breast cancer. This study explores the effect of different exercise time combined with active peptide-modified drug-loaded nano-drug delivery system on breast cancer targeting; it aims to find ways to promote the effect of drug targeted therapy, and provide the role of exercise in tumor targeted therapy new basis. In this study, a comprehensive therapy of drugs combined with exercise was applied to nude mice bearing breast cancer Bcap-37 to observe the effect of exercise on drug treatment. The results of the study found that the exercise combined with PLA-PLL-RGD nano drug delivery system group was statistically significant compared with the exercise group and the saline group (p<0.05). Exercise with different exercise time can significantly promote the targeting effect of PLA-PLL-RGD nano drug delivery system on breast cancer tissue neovascularization. It shows that doing appropriate exercise while targeting tumor therapy can help increase targeted drugs to reach the tumor site, and can effectively inhibit tumor growth. Popularizing it in breast cancer treatment will help improve the recovery rate of patients.
Athletic Sports, Nanoparticle Drug Delivery System, Breast Cancer, Tumor Targeting
Miaohong Gao. Sports on the Curative Effect of Breast Cancer Drug-Loaded Nanoparticle Drug Delivery System. International Journal of Sports Technology (2022), Vol. 3, Issue 4: 64-78. https://doi.org/10.38007/IJST.2022.030405.
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