Welcome to Scholar Publishing Group

International Journal of Health and Pharmaceutical Medicine, 2022, 3(4); doi: 10.38007/IJHPM.2022.030407.

Research progress of Huangqi Guizhi Wuwu Decoction in the treatment of lumbar protrusion

Author(s)

Shaotun Guo and Yingang Li

Corresponding Author:
Yingang Li
Affiliation(s)

Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine, Xianyang 712000, Shaanxi, China

Abstract

Astragalus Guizhi Wuwu Decoction is a special prescription for treating blood arthralsis in Zhang Zhongjing's Synopsis of the Golden Chamber. According to the theory of traditional Chinese medicine, it has the effects of regulating and nourishing the health, qi and blood.Modern experimental studies have confirmed that it has many effects, such as immune regulation, influence on hemorheology, anti-oxidative damage, promote nerve repair, inhibit inflammation and oxidative stress, etc. The author's instructor and folk traditional Chinese medicine use Huangqi Guizhi Wuwu decoction can often achieve good curative effect, but the relevant experimental studies are few. Therefore, from the perspective of clinical application, we summarize the experience of others in the treatment of lumbar disc herniation with this prescription, so as to provide reference for subsequent clinical application and experimental research.

Keywords

Lumbar Disc Herniation, Huangqi Guizhi Wuwu Decoction, Minimally Invasive Surgery, Foraminal Endoscopic Nucleus Pulposus Extraction, Chinese Medicine Treatment

Cite This Paper

Shaotun Guo and Yingang Li. Research progress of Huangqi Guizhi Wuwu Decoction in the treatment of lumbar protrusion. International Journal of Health and Pharmaceutical Medicine (2022), Vol. 3, Issue 4: 80-90. https://doi.org/10.38007/IJHPM.2022.030407.

References

[1] Zhang H, Dong B Q. Clinical research overview of traditional Chinese medicine and western medicine in the treatment of lumbar disc herniation. Journal of Practical Traditional Chinese Medicine Internal Medicine, 2019, 33(1): 75-77. https://doi.org/10.26549/yzlcyxzz.v3i5.5266

[2] Zhou MW, Yue Shouwei, He Chengqi, et al. Chinese expert consensus on rehabilitation treatment of lumbar disc herniation. Chinese Journal of Rehabilitation Medicine, 2017, 32(2): 129-135. DOI:10.3969/j.issn.1001-1242.2017.02.001

[3] Cheng Zhi-Xiang, Zheng Yong-Jun, Feng Zhi-Ying, et al. Chinese Association for the Study of Pain: Expert consensus on diagnosis and treatment for lumbar disc herniation. World Journal of Clinical Cases, 2021, 9(9): 2058-2067.

[4] Huo C L, Li H, Xu W, et al. Research progress on the combination of internal and external medicine of traditional Chinese medicine in the treatment of lumbar disc herniation. Chinese Journal of Ethnic Folk Medicine, 2021, 30(15): 74-77, 83. https://doi.org/10.26549/yzlcyxzz. v3i5.5266

[5] Chen Zhiwei's. Experience in treating lumbar disc herniation with classical prescription. New Chinese Medicine, 2010, 42(11): 140-141. 

[6] Chang Zheng, Liu Zhijun. Professor Liu Zhijun's academic experience in treating "numbness" of bone injury and injury. Chinese Journal of Traditional Chinese Medicine Orthopedics, 2021, 29(7): 77-79.

[7] Fu Bifeng. Clinical effect of Huangqi Guizhi Wuwu decoction on lumbar disc herniation (Qi deficiency and blood stasis syndrome). Hunan University of Traditional Chinese Medicine, 2018.

[8] Huang Qi Guizhi Wuwu Decoction in treating 30 cases of numbness in Department of orthopedics. Jiangxi Traditional Chinese Medicine, 1996(6): 40. 

[9] Bear Deng. Effect of modified Huangqi Guizhi Wuwu decoction on residual lower limb numbness after decompression of lumbar disc herniation. Jiangxi University of Traditional Chinese Medicine, 2020.

[10] Huang YF, Dong ZY. Treatment of 54 cases of numbness syndrome after lumbar disc herniation with Huangqi Guizhi Wuwu Decoction. Henan Traditional Chinese Medicine, 2008, 196(4): 19-20. https://doi.org/10.26549/ajcm.v4i2.6668

[11] Liu Zuyi, Wu Dhua, Liu Fang, et al. Experience of treating numbness by combining disease and syndrome. Journal of Hunan University of Traditional Chinese Medicine, 2020, 40(1): 1-4.

[12] Li Yanmin, Li Yanmin, Li Yanmin. Study on the formulation of Huangniu Bailong Decoction for the treatment of lumbar disc herniation. Journal of Shaanxi University of Traditional Chinese Medicine, 2018, 41(6): 39-41. https://doi.org/10.26549/yzlcyxzz.v1i1.1375

[13] Jia X X, Xu B, Xu T, et al. Quadruple therapy for 28 cases of lumbar disc herniation. Inner Mongolia Journal of Traditional Chinese Medicine, 2016, 35(1): 5-6.

[14] Chi Hongwan. Effect of electroacupuncture combined with Huangqi Guizhi Wuwu decoction on residual neurological function impairment after lumbar disc herniation. Clinical Practice of Integrated Traditional Chinese and Western Medicine, 2021, 21(16): 33-34, 69.

[15] Huang Qi Guizhi Wuwu decoction combined with acupuncture in the treatment of blood stasis type lumbar disc herniation. Clinical Journal of Traditional Chinese Medicine, 2020, 32(4): 688-691. (in Chinese with English abstract) https://doi.org/10.26549/ajcm.v4i2.6668

[16] Mo Jun, Huang Yifei. Huangqi Guizhi Wuwu decoction combined with acupuncture and moxibustion in the treatment of residual symptoms after lumbar spine surgery. Xinjiang Traditional Chinese Medicine, 2016, 34(1): 61-62.

[17] Zheng Yanhui. 41 cases of upper limb numbness caused by cervical spondylosis were treated with Huangqi Guizhi Wuwu Decoction and Siwu Decoction  Guangming Traditional Chinese Medicine, 2011, 26 (12): 2456-2456

[18] Liang Zhenhong. Analysis of 68 cases of lumbar disc herniation treated with Huangqi Guizhi Wuwu decoction. Journal of Chinese Medicine, 2003(4): 603-616. (in Chinese with English abstract)

[29] He X F, Dong Z Y, Mo J, et al. Lumbar short lever fixed point oblique rotation combined with Huangqi Guizhi Wuwu decoction in the treatment of failure syndrome after lumbar spine surgery. Xinjiang Traditional Chinese Medicine, 2019, 37(4): 33-34.

[20] Liu G H. Clinical observation of Huangqi Guizhi Wuwu decoction combined with percutaneous foraminal endoscopic nucleus pulposus extraction in the treatment of lumbar disc herniation. Strait Pharmacy, 2018, 30(8): 140-141.

[21] Xie Hai-liang. A short-term follow-up study of Huangqi Guizhi Wuwu decoction combined with percutaneous foraminal endoscopic discectomy for 42 cases of lumbar disc herniation. Northern Pharmacy, 2018, 15(11): 69-70.

[22] Wang Y, Wang Y, Wang Y, et al. Clinical study on the treatment of lumbar disc herniation with Huangqi Guizhi Wuwu decoction combined with foraminal endoscopic treatment. Modern Distance Education of Chinese Medicine, 2016, 14(4): 94-96.

[23] Zhang J, Hao D J, Wu G Q, et al. Clinical efficacy of sacral canal block combined with Huangqi Guizhi Wuwu decoction in the treatment of lumbar disc herniation. World Medical Information Digest, 2016, 16(65): 26, 84.

[24] Hu W, Liu Y L, Wang R, et al. Clinical study of percutaneous foraminoscopy combined with Huangqi Guizhi Wuwu decoction in the treatment of lumbar disc herniation. New Chinese Medicine, 2015, 47(9): 125-127.

[25] Yang Jingbo. Sacral canal block combined with Huangqi Guizhi Wuwu decoction for 40 cases of lumbar disc herniation. Journal of Shaanxi University of Traditional Chinese Medicine, 2015, 38(6): 70-71, 90.

[26] Sun X, BazL, Ni J P, et al. Treatment of low back lumbar disc herniation with traditional Chinese medicine combined with endoscopic technique. Chin J Orthopedics of Traditional Chinese Medicine, 2015, 23(9): 43-45.

[27] Dong Z Y, Chen J Z, HU H F. Efficacy evaluation of combined application of Huangqi Guizhi Wuwu decoction and sodium hyaluronate after MED. Xinjiang Traditional Chinese Medicine, 2007, 111(5): 31-32.

[28] KeMing. Effect of modified Huangqi Guizhi Wuwu decoction on postoperative lumbar function recovery in patients with lumbar disc herniation. Medical Equipment, 2020, 33(14): 111-112.

[29] Huang Y F, He C X, et al. Treatment of numbness syndrome after lumbar disc herniation with Huangqi Guizhi Wuwu decoction: a report of 126 cases. Xinjiang Journal of Chinese Medicine, 2007, 110(4): 28-29. https://doi.org/10.26549/ajcm.v4i2.6668

[30] Wei T T, Huang X X, Li L R, et al. Research progress of traditional Chinese medicine in the treatment of lupus nephritis. Hunan Journal of Traditional Chinese Medicine, 2021, 37(9): 194-196. (in Chinese)

[31] Wang Q, Chen Q, Li C G, et al. Effect of acupuncture combined with modified Huangqi Guizhi Wuwu decoction on nerve conduction velocity in patients with diabetic peripheral neuropathy. Zhejiang Journal of Traditional Chinese Medicine, 2021, 56(8): 604-605.

[32] Bai Qing. Effect of Huangqi Guizhi Wuwu Decoction on diabetes peripheral neuropathy and the influence of nerve conduction velocity. Chinese patent medicine, 2015, 37 (5): 3

[33] Tian M, Shuai Y, Li X, et al. Meta-analysis of clinical efficacy and safety of Huangqi Guizhi Wuwu decoction combined with chemical drugs in the treatment of rheumatoid arthritis. Chinese Journal of Immunology, 2021, 37(16): 1964-1966.

[34] Zhu L, Zhang Z, Shen J, et al. Effect of Astragalus Guizhi Wuwu decoction in the treatment of chemotherapy-related peripheral neuritis. China Practical Medicine, 2021, 16(25): 175-178.

[35] Zheng Ruwen. Treatment of 32 cases of thromboangiitis obliterans with modified Huangqi Guizhi Wuwu decoction. Chinese Journal of Traditional Chinese Medicine Emergency, 2009, 18(6): 987-988.

[36] Huo LY,Feng TX,Fu BF, et al. Potential Mechanism of Huangqi Guizhi Wuwu Decoction for Cervical Spondylosis Treatment Based on Network Pharmacology. Tmr Integrative Medicine, 2021, 5(21).

[37] Weiwei L, Liqiang S, Qiang W, et al. Huangqi Guizhi Wuwu Decoction Attenuates Podocyte Cytoskeletal Protein Damage in Iga Nephropathy Rats By Regulating At1r/nephrin/c-abl Pathway. Biomedicine & Pharmacotherapy, 2021, 142.

[38] Wei P, Xu D T, Chen Y F, et al. Pharmacodynamic study of Huangqi Guizhi Wuwu decoction on sciatica in rats. Science Technology and Engineering, 2016, 16(19): 170-173.

[49] Study on the mechanism of Huangqi Guizhi Wuwu decoction on collagen-induced arthritis in rats. Shanxi Traditional Chinese Medicine, 2017, 33(1): 52-54. (in Chinese with English abstract)

[40] Li Shuyi, Zhao Zhiqiang, Zhang Qingbo, etc. In vitro study on the effect of total flavonoids in Astragalus Guizhi Wuwu decoction on immune function of mice. Hebei Journal of Traditional Chinese Medicine, 2014, 36(3): 432-434. https://doi.org/10.14725/gjicmwm.v3n1a1083

[41] Wang Y, Wu Y, Ye Y, et al. Protective effect of Huangqi Guizhi Wuwu decoction on myocardial ischemia-reperfusion injury in rats. Shanghai Journal of Traditional Chinese Medicine, 2015, 49(10): 80-83.

[42] Zhangming L, Jiayun S, Xuejiao G, et al. Herbal Formula Huangqi Guizhi Wuwu Decoction Attenuates Paclitaxel-related Neurotoxicity Via Inhibition of Inflammation and Oxidative Stress.. Chinese Medicine, 2021, 16(1).

[43] ZHAO L, LI Y Y, WANG Y H, et al. Effect of Huangqi Guizhi Wuwu decoction on angiogenesis in rats with osteoarthritis. Chinese Journal of Experimental Formulae, 2019, 25(3): 87-93. https://doi.org/10.26549/yzlcyxzz.v3i3.3920