Panpan Guo, Xiaowen Jia, Jie Guo, Youyu She and Tong Qian
Xidian Group Hospital, Xi’an 710077, China
We usually use drugs to promote cervical ripening before inducing labor to reduce the risk of induction failure and surgical delivery. The methods to promote cervical ripening are developed rapidly, and there are many types, each with its own advantages and disadvantages. In recent years, the role of nitric oxide (NO) donors in promoting cervical ripening has become a research hotspot. Its representative drugs are mainly isosorbide mononitrate; ISMN), glyceryl trinitrate, sodium nitroprusside, etc. This article analyzes and summarizes the historical background, mechanism of action and clinical application of NO donors to promote cervical ripening.
NO Donors, Isosorbide Mononitrate, Cervical Ripening, Bishop Score
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