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International Journal of World Medicine, 2023, 4(2); doi: 10.38007/IJWM.2023.040210.

Advances in Cellular Immune Mechanisms of Atopic Dermatitis

Author(s)

Jianghui Li, Xiaoning Yan, Haoyuan Hu

Corresponding Author:
Xiaoning Yan
Affiliation(s)

Shaanxi Provincial Hospital of Chinese Medicine, Xi'an 710003, Shaanxi, China

Abstract

Atopic dermatitis is a common chronic inflammatory skin disease with severe itching as the most obvious clinical symptom. Its immunological mechanism is very complex, involving the participation of multiple immune cells and their cytokines, chemokines, pro-inflammatory molecules and other immune cascades. At the same time, it is related to skin barrier destruction, decreased expression of antimicrobial peptides, and immune-nervous system crosstalk. This article mainly reviews the various cells, cytokines and their cascades in the immune-related pathogenesis of atopic dermatitis, in order to provide corresponding theoretical basis for the treatment of atopic dermatitis.

Keywords

Atopic Dermatitis, Immune Mechanism, Inflammation, Cytokines

Cite This Paper

Jianghui Li, Xiaoning Yan, Haoyuan Hu. Advances in Cellular Immune Mechanisms of Atopic Dermatitis. International Journal of World Medicine (2023), Vol. 4, Issue 2: 81-92. https://doi.org/10.38007/IJWM.2023.040210.

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