Peiru Wang, Dongmei Yu, Shanshan Chen, Dewen Huang
Department of Medicine, The First People's Hospital of Lanzhou New District, Lanzhou New District730314, Gansu, China
Analyze the prognosis, survival status, and risk factors of occupational pneumoconiosis patients in Lanzhou area.Methods:100 pneumoconiosis patients hospitalized in our hospital from December 2022 to January 2023 were selected as the research subjects, including 67 male patients and 13 female patients; Initial diagnosis period: 77 cases in the first stage, 16 cases in the second stage, and 7 cases in the third stage. According to survival or not, they were divided into a survival group of 85 cases and a death group of 15 cases. A self-made survey questionnaire was used to collect patients' age, gender, occupational history, smoking history, past medical history, current medical history, complications, and other information. Patients were followed up for 1 year to understand their prognosis and survival status. They were divided into survival group and death group based on survival for comparative analysis. Logistic regression analysis was used to determine the risk factors for mortality after occupational pneumoconiosis. The prevalence rate was higher in the age group of 50-69, with 66 cases (66.00%), 23 cases (23.00%) aged 70-80, and 11 cases (11.00%) aged 30-49; 77 cases (77.00%) in the first stage, 16 cases (16.00%) in the second stage, and 7 cases (7.00%) in the third stage of the staging; Coal workers' pneumoconiosis was the main cause of pneumoconiosis in 87 cases (87.00%), followed by silicosis in 9 cases (9.00%), with a statistically significant difference (P<0. 05) 05)｡ The results of univariate analysis showed that exposure to dust, smoking history, presence or absence of comorbidities, advanced stage of pneumoconiosis, initial diagnosis stage, and type of pneumoconiosis were the single factors affecting the prognosis and mortality of patients with chronic pneumoconiosis (P<0.05); Gender and age are not single factors that affect the prognosis and mortality of patients with chronic pneumoconiosis (P>0.05). The survival state variable is whether occupational pneumoconiosis patients die from pneumoconiosis or its complications during the observation period (0=no, 1=yes), and the observation time is the survival time variable. The time dependent variable is the length of work exposed to dust (≤ 10 years=1,>10 years=2), smoking history (yes=1, no=0), comorbidities (yes=1, no=0), and advanced stage of pneumoconiosis (yes=1, no=0). The time dependent variable is the initial diagnosis stage (first stage=1, second stage=2, third stage=3) The type of pneumoconiosis (silicosis=1, coal worker's pneumoconiosis=2, other pneumoconiosis=3), age (≤ 50 years of age=1,>50 years of age=2) are independent variables. Multiple categorical variable are transformed into dummy variables for analysis. The hazard ratio (HR) of variables and its 95% confidence interval are calculated using the forward method of non proportional risk Cox regression model. The results showed that exposure to dust, smoking history, presence or absence of comorbidities, advanced stage of pneumoconiosis, initial diagnosis stage, and type of pneumoconiosis were the influencing factors for the survival time of occupational pneumoconiosis patients (P<0.05). The prognosis and survival of patients with chronic pneumoconiosis are poor, and exposure to dust, smoking history, presence or absence of comorbidities, advanced stage of pneumoconiosis, initial diagnosis stage, and type of pneumoconiosis are independent risk factors that affect the prognosis and death of patients with chronic pneumoconiosis. Special attention should be paid to workers with risk factors, and timely health examinations should be conducted to achieve early detection and treatment; Actively treating comorbidities and quitting smoking can effectively improve patient prognosis.
Occupational Pneumoconiosis, Prognostic Survival Status, Multiple Factors
Peiru Wang, Dongmei Yu, Shanshan Chen, Dewen Huang. Analysis of Prognosis, Survival Status, and Risk Factors of Occupational Pneumoconiosis Patients in Lanzhou Area. International Journal of World Medicine (2023), Vol. 4, Issue 3: 1-10. https://doi.org/10.38007/IJWM.2023.040301.
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