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International Journal of Health and Pharmaceutical Medicine, 2020, 1(1); doi: 10.38007/IJHPM.2020.010104.

Incomplete Ischemia-reperfusion on Skin Pressure Sores in Rats and Its Mechanism


Quella Fernando

Corresponding Author:
Quella Fernando

Simon Fraser University, Canada


Pressure ulcers are called "bed sores" in the field of traditional Chinese medicine. Long-term bedridden, especially the elderly lying passively, are prone to cause severe skin contact pressure sores, which seriously affects the quality of life of patients. With the development and development of high-end medical equipment, people can now easily achieve incomplete ischemia-reperfusion, but the role of incomplete ischemia-reperfusion in skin pressure ulcers is not well documented and unclear. In order to investigate the effect and mechanism of incomplete ischemia-reperfusion on skin pressure ulcers in rats, this study set up 2 groups, using a controlled experiment method, randomly divided 120 rats of simulated patients into 2 groups, each group For 60 animals, the experimental group used incomplete ischemia-reperfusion to observe the changes of patients' cells through continuous observation, and gave corresponding plans. The control group used common treatment methods. The results show that incomplete ischemia-reperfusion can aggravate early skin contact surface pressure ulcers in bedridden patients. The detection effective rate is 81.2%, and the incidence of skin contact surface pressure ulcers is 89.31% and 11.27%, respectively. Preventing incomplete ischemia-reperfusion during preventive care of patients can greatly reduce the incidence of pressure ulcers on the skin contact surface and can be popularized and applied.


Incomplete Ischemia-reperfusion, Long Term Bedridden Patients, Pressure Sores on Skin Contact Surface, Preventive Care

Cite This Paper

Quella Fernando. Incomplete Ischemia-reperfusion on Skin Pressure Sores in Rats and Its Mechanism. International Journal of Health and Pharmaceutical Medicine (2020), Vol. 1, Issue 1: 38-49. https://doi.org/10.38007/IJHPM.2020.010104.


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