Pressure ulcers are called "bed sores" in the field of traditional Chinese medicine. Long-term bedridden, especially the elderly lying passively, are prone to cause severe skin contact pressure sores, which seriously affects the quality of life of patients. With the development and development of high-end medical equipment, people can now easily achieve incomplete ischemia-reperfusion, but the role of incomplete ischemia-reperfusion in skin pressure ulcers is not well documented and unclear. In order to investigate the effect and mechanism of incomplete ischemia-reperfusion on skin pressure ulcers in rats, this study set up 2 groups, using a controlled experiment method, randomly divided 120 rats of simulated patients into 2 groups, each group For 60 animals, the experimental group used incomplete ischemia-reperfusion to observe the changes of patients' cells through continuous observation, and gave corresponding plans. The control group used common treatment methods. The results show that incomplete ischemia-reperfusion can aggravate early skin contact surface pressure ulcers in bedridden patients. The detection effective rate is 81.2%, and the incidence of skin contact surface pressure ulcers is 89.31% and 11.27%, respectively. Preventing incomplete ischemia-reperfusion during preventive care of patients can greatly reduce the incidence of pressure ulcers on the skin contact surface and can be popularized and applied.

Quella Fernando. Incomplete Ischemia-reperfusion on Skin Pressure Sores in Rats and Its Mechanism. International Journal of Health and Pharmaceutical Medicine (2020), Vol. 1, Issue 1: 38-49. https://doi.org/10.38007/IJHPM.2020.010104.

[1] Levine, J. M. (2018). “100 Years of Bedsores: How Much Have We Learned?, Advances in Skin & Wound Care”, 31(3), pp.139-141. DOI: 10.1097/01.ASW.0000530066.59878.2b

[2] Iodence AE, Olsen AM, McGilvray KC, Duncan CG, & Duerr FM. (2018). “Use of Pressure Mapping for Quantitative Analysis of Pressure Points Induced by External Coaptation of the Distal Portion of the Pelvic Limb of Dogs”, American Journal of Veterinary Research, 79(3), pp.317-323. DOI: 10.2460/ajvr.79.3.317

[3] Yazici, D. T. & Yener, A. (2019). “Processing Polymer Nanocomposites with Natural Additives for Medical Applications”, Journal of polymer engineering, 39(2), pp.178-185.

[4] Lin, Y. Xu, H. Dong, B.Sun, X. Li, C, & Li, J. et al. (2017). “Amphiphilic Silane Modified Multifunctional Nanoparticles for Ratiometric Oxygen Sensing”, Rsc Adv, 7(54), pp.34118-34124.

[5] Jaffe, & Elaine, S. (2017). “The Microscope as a Tool for Disease Discovery—a Personal Voyage”, Annual Review of Pathology Mechanisms of Disease, 12(1), pp.1-24.

[6] Temiz, Y. (2020). “The Lego Microscope: a Valuable Lab Tool Began as a Diy Project - [hands on], IEEE Spectrum”, 57(5), pp.16-18. DOI: 10.1109/MSPEC.2020.9078448

[7] Derek H. Craston, Charles W. Lin, & Allen J. Bard. (2016). “High Resolution Deposition of Silver in Nafion Films with the Scanning Tunneling Microscope”, metallurgical analysis, 135(3), pp.66-68.

[8] G. Binnig, C. F. Quate, & Ch. Gerber. (2018). “Atomic Force Microscope”, Journal of materials engineering, 56(9), pp.930-933. DOI: 10.1007/978-981-10-6156-1_6

[9] Yang, S. J. Berndl, M. Michael Ando, D. Barch, M. Narayanaswamy, A. & Christiansen, E. et al. (2018). “Assessing Microscope Image Focus Quality with Deep Learning”, BMC Bioinformatics, 19(1), pp.77.

[10] Remy Neris, O. (2017). “Vhipod, Individual Transport Vehicle Standing Self-balancing Station for Disabled Person with Standing Aid, Anr”, Impact,2017(4), pp.80-82.

[11] Jahan-Tigh, R. R. Chinn, G. M. & Rapini, R. P. (2016).“A Comparative Study Between Smartphone-based Microscopy and Conventional Light Microscopy in 1021 Dermatopathology Specimens”, Archives of Pathology & Laboratory Medicine, 140(1), pp.86-90.

[12] Aguaron, J. Teresa Escobar, M. & Maria Moreno-Jimenez, J. (2016). “The Precise Consistency Consensus Matrix in a Local AHP-Group Decision Making Context”,  Annals of Operations Research, 245(1-2),pp. 245-259.