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International Journal of Health and Pharmaceutical Medicine, 2021, 2(1); doi: 10.38007/IJHPM.2021.020102.

Laser Scanning Confocal Microscopy Study on Intracellular Calcium Changes in Rat Myocardium after Endurance Training and Suspension


Bijaya Ketan Panigrahi

Corresponding Author:
Bijaya Ketan Panigrahi

University of Gottingen, Germany


Long-term high-intensity physical training will cause the heart of athletes to be prone to myocardial strain due to a state of oppression. How to scientifically and rationally plan the endurance training time and intensity of athletes to ensure the health of athletes has always been a sports coach. And the hot issues concerned by various biomedical scientists. To this end, this article uses laser scanning confocal microscopy to study the changes of calcium ions in rat cardiomyocytes after endurance training and suspension training, with the purpose of specifically analyzing the mechanism of changes in the structure and function of the sports heart to provide scientific planning for athletes’ endurance training theoretical reference. In this paper, 40 adult male SD rats were selected as experimental objects. After one week of normal feeding, they were randomly divided into 12 endurance training groups, 8 training control groups, 12 suspension training groups, and 8 suspension control groups. Animal training model was established and intracellular calcium samples were prepared. Then, the laser scanning confocal microscope was used to observe the changes of calcium ion in each group. The final result is that endurance training is beneficial to the proliferation and division of myocardial cells; different training cycles and suspension cycles have a greater impact on calcium ion concentration, the longer the training time, the greater the intracellular calcium ion concentration in the myocardium, and with the extension of the suspension period, the rate of decrease in calcium ion concentration also increases accordingly; endurance training does not have much effect on the body's hematological indicators (P>0.05); endurance training is conducive to improving calcium ion intake and release of myocardial sarcoplasmic reticulum and ATPase activity of calcium ion. The results of the study prove that calcium changes in cardiomyocytes are important signals for changes in cardiac structure and function.


Laser Scanning Confocal Microscope, Endurance Training, Rat Cardiomyocyte, Calcium Lons

Cite This Paper

Bijaya Ketan Panigrahi. Laser Scanning Confocal Microscopy Study on Intracellular Calcium Changes in Rat Myocardium after Endurance Training and Suspension. International Journal of Health and Pharmaceutical Medicine (2021), Vol. 2, Issue 1: 12-24. https://doi.org/10.38007/IJHPM.2021.020102.


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