To study the clinical value of minimally invasive laparoscopic treatment for colorectal cancer, and to analyze the clinical effect of minimally invasive laparoscopic treatment for colorectal cancer. According to our hospital in June 2019 to December 2019 were analyzed the clinical data of 124 patients with colorectal cancer contrast research, according to the operation method 124 patients were divided into control group and experimental group and control group including 62 cases of colorectal cancer patients, they all use conventional surgery treatment, the conventional surgery group; The experimental group included 62 patients with colorectal cancer, all of whom were treated with laparoscopic minimally invasive surgery, namely the laparoscopic minimally invasive treatment group. Age, sex, initial score at admission, grade of illness at admission, SAH Fisher grade at admission, intraoperative blood loss, operative time, postoperative hospital stay, complication rate, and tumor metastasis rate were observed in the two groups. In 62 patients data contrast analysis, two groups of patients in age, sex, when the initial score on admission, admission condition grading situation, SAH Fisher on admission grade five aspects: there is no difference (P>0.05), and how much the intraoperative blood loss, operating time length, length of postoperative hospital stay, complications, and two groups of patients with metastatic rate five aspects data showing a statistically significant difference (P<0.05). The minimally invasive laparoscopic treatment of colorectal cancer is significantly better than the conventional surgical treatment of colorectal cancer, the application of minimally invasive laparoscopic treatment of colorectal cancer patients can speed up the recovery of patients, reduce the incidence of complications.

Xiaofen Fan. Clinical Value of Minimally Invasive Laparoscopic Treatment of Colorectal Cancer. International Journal of Health and Pharmaceutical Medicine (2021), Vol. 2, Issue 2: 1-12. https://doi.org/10.38007/IJHPM.2021.020201.

[1] Lambat E S, Pluchino N, Petignat P. (2019). “Cell Spillage after Contained Electromechanical Morcellation Using a Specially Designed In-Bag System for Laparoscopic Myomectomy: Prospective Cohort Pilot Study”, Journal of Minimally Invasive Gynecology, 26(7), 1351-1356. DOI: 10.1016/j.jmig.2019.01.014

[2] Lee Y I, Lim Y S, Park H S. (2015). “Colorectal Neoplasms in Relation to Non-alcoholic Fatty Liver Disease in Korean Women: A Retrospective Cohort Study”, J Gastroenterol Hepatol, 27(1), 91-95. DOI: 10.1111/j.1440-1746.2011.06816.x

[3] Ward R L, Todd A V, Santiago F. (2015). “Activation of the K-ras Oncogene in Colorectal Neoplasms is Associated with Decreased Apoptosis”, Cancer, 79(6), 1106-1113. DOI: 10.1002/(SICI)1097-0142(19970315)79:6<1106::AID-CNCR8>3.0.CO;2-D

[4] Baldus S E, Hanisch F G, Kotlarek G M, et al. (2015). “Coexpression of MUC1 Mucin Peptide Core and the Thomsen-Friedenreich Antigen in Colorectal Neoplasms”, Cancer, 82(6), 1019-1027. DOI: 10.1002/(SICI)1097-0142(19980315)82:63.0.CO;2-9

[5] Mcgill S K, Soetikno R M, Rouse R V, et al. (2015). “970 High Rate of Advanced Neoplasia At Surveillance in Patients With Nonpolypoid (Flat and Depressed) Colorectal Neoplasms: Longitudinal Matched Cohort Study”, Gastrointestinal Endoscopy, 81(5), AB182-AB182. DOI: 10.1016/j.cgh.2016.08.045

[6] Vanessa E, Megha B, Petra S K, et al. (2018). “Metabolomics Biomarkers for Detection of Colorectal Neoplasms: A Systematic Review”, Cancers, 10(8), 246. DOI: 10.3390/cancers 10080246

[7] He Y Q, Wang X, Li A Q, et al. (2015). “Factors for Endoscopic Submucosal Dissection in Early Colorectal Neoplasms: A Single Center Clinical Experience in China”, Clinical Endoscopy, 48(5), 405-410. DOI: 10.5946/ce.2015.48.5.405

[8] Kim B, Kim Y H, Park S J, et al. (2017). “Probe-based Confocal Laser Endomicroscopy for Evaluating the Submucosal Invasion of Colorectal Neoplasms”, Surgical Endoscopy, 31(2), 594-601. DOI: 10.1007/s00464-016-5003-x

[9] Youk E G, Sohn D K, Hong C W, et al.(2016). “Early Outcomes of Endoscopic Submucosal Dissection for Colorectal Neoplasms According to Clinical Indications”, Diseases of the Colon & Rectum, 59(5), 403. DOI: 10.1097/DCR.0000000000000549

[10] Carter J V, Roberts H L, Pan J, et al. (2016). “A Highly Predictive Model for Diagnosis of Colorectal Neoplasms Using Plasma MicroRNA: Improving Specificity and Sensitivity”, Annals of Surgery, 264(4), 575. DOI: 10.1097/SLA.0000000000001873

[11] Bae J H, Yang D H, Lee J Y, et al.(2016). “Clinical Outcomes of Endoscopic Submucosal Dissection for Large Colorectal Neoplasms: A Comparison of Protruding and Laterally Spreading Tumors”, Surgical Endoscopy, 30(4), 1619-1628. DOI: 10.1007/s00464-015-4392-6

[12] Hong M J, Kim J H, Lee S Y, et al.(2015). “Prevalence and Clinical Features of Coagulation Syndrome after Endoscopic Submucosal Dissection for Colorectal Neoplasms”, Digestive Diseases & ences, 60(1), 211-216. DOI: 10.1007/s10620-014-3484-9