Against the backdrop of the impact of e-commerce, consumption upgrading and the surging demand for health services, the transformation of shopping centers into medical complexes has become an important path for the innovation of commercial real estate. Focusing on this emerging business format, this paper constructs an integrated analytical framework of "Driving-Innovation-Governance" by adopting the methods of literature analysis and multi-case comparison. The study finds that the transformation is the result of the synergistic driving of factors such as e-commerce pressure, the transformation of real estate capital, population aging and the empowerment of the sharing economy, and its core innovation lies in building a cross-border ecosystem of "medical service-driven passenger flow - commercial consumption conversion". However, this model still faces four major governance challenges: the lag of policy supervision adaptation, the mismatch between economic costs and payment systems, the difficulty in breaking social trust barriers, and the dilemma of balancing data security and value mining. In response, the study proposes systematic countermeasures such as the introduction of a "regulatory sandbox", the construction of a diversified payment ecosystem, the promotion of transparent brand building, and the establishment of a data governance framework. This research provides a theoretical perspective for understanding the cross-border integration of commercial real estate and also offers practical guidance for the sustainable development of medical complexes.

Chaoqun Ma. Research on the Cross-border Integration Mechanism and Governance Path of Medical Complexes. International Journal of World Medicine (2026), Vol. 7, Issue 1: 1-7. https://doi.org/10.38007/IJWM.2026.070101.

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