As an early warning system for the long-term toxic effects of pollutants, multiple biomarkers have been widely used in environmental monitoring and evaluation. Based on the multi biomarker pollution index(MBPI) method, this paper proposes the autocorrelation topological index(ATI), and analyzes the quantitative relationship(QR) between it and the biological activity of organic substances. Firstly, the MBPI method is briefly introduced, and the quantitative analysis of organic organisms in the MBPI method is carried out, with emphasis on the GC-MS detection and analysis of organic substances; Then, the calculation method of ATI is proposed and analyzed; Finally, through the topological index method, taking penicillin as an example, the QR of its biological activity is discussed, which has important guiding significance for the future study of organic pollution.

Ginty Annie. Quantitative Relationship between Autocorrelation Topological Index and Biological Activity of Organic Compounds based on Multi Biomarker Pollution Index Method. Academic Journal of Environmental Biology (2020), Vol. 1, Issue 1: 36-43. https://doi.org/10.38007/AJEB.2020.010105.

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