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International Journal of Health and Pharmaceutical Medicine, 2022, 3(3); doi: 10.38007/IJHPM.2022.030301.

Determination of Pasma Procalcitonin and Its Application in Sepsis Infection


Wenbo Zhang

Corresponding Author:
Wenbo Zhang

Department of Respiratory and Critical Care Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan, China



Infectious diseases are a common disease in clinic. The incidence rate is high every year, and the infected patients will suffer from septic shock. Sepsis is a common cause of death. Generally speaking, sepsis is a systemic inflammatory response of the host to infection, with certain characteristics such as questioning and heart rate. If patients with sepsis are diagnosed and treated in the early stage, the mortality of such diseases can be greatly reduced. PCT is the precursor of calcitonin. PCT is specific for bacterial infection and can help to judge viral infection and bacterial infection. Based on this, this article through the investigation and research to understand the determination method of plasma procalcitonin, establish the reaction mode based on immune chromatography technology in time-resolved technology, and combine it with sepsis infection. By analyzing the plasma procalcitonin level of patients with positive blood culture, the optimal critical value of PCT was 1.34 μ g / ml. Then the PCT level of patients with sepsis and severe sepsis was analyzed, and the optimal critical value of PCT for diagnosis of sepsis and severe sepsis was 1.09 μ g / ml. Through this experiment, we determined the characteristics of procalcitonin in patients with sepsis and provided a reference method for the application of procalcitonin in sepsis infection.


Plasma Procalcitonin, Sepsis Infection, Immunochromatography Technology, Time Resolution

Cite This Paper

Wenbo Zhang. Determination of Pasma Procalcitonin and Its Application in Sepsis Infection. International Journal of Health and Pharmaceutical Medicine (2022), Vol. 3, Issue 3: 1-13. https://doi.org/10.38007/IJHPM.2022.030301.


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